New to this really could use a whole lotta feedback on what to do here

Never dabbled before, but I recently came across 16 HP Prodesk 400 G7 with 16gb ram, i5, AMD Radeon™ RX 550X Graphics (4 GB GDDR5, LP, DisplayPort, HDMI, PCIe x16), 256gb ssd.

Can these be utilized to mine and if so how would one go about setting 16 of these up?

Thanks and please explain to me like Im a five year old kid driving crayons in my nostrils and flinging speghetti.

Nicehash.com. It will do almost all the work off you.

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Sadly 4GB GPUs can’t mine as much so will have a limited life span for mining though with the multitude of coins I am sure there are options to mine but not sure about profitably. I would expect to find more profit in flipping those on the 2ndary market or parting out.